Basic protocol


Applying Hyperoil® always involves three simple steps:

  • CLEANSE (clean the wound)
  • COVER with a protective or absorbent protective bandage

These three actions are to be repeated each time the medication is applied, to various degrees and using various methods.

The APPLICATION FREQUENCY OF THE MEDICATION depends on the condition of the lesion and on the STAGE of the lesion (below are some suggested guidelines):

CLEANSING STAGE - less frequent (every 3-7 days)
GRANULATION STAGE - very frequent (every 12h/1-2 days)
REEPITHELIALIZATION STAGE - frequent (every 2-4 days)





These products are not required. Moreover, they partly or completely cancel out the action of Hyperoil®!

1. RINSE the wounds with plenty of sterile saline solution using a sterile 20cc syringe without needle. Hyperoil® GAUZES can also be used to clean the wound (instead of saline solution).

If you choose to use gauzes, GENTLY PAD the whole WOUND DIRECTLY with Hyperoil® GAUZES. As soon as the Hyperoil® GAUZE used to pad the wound appears soiled, discard it and replace with a fresh one. Proceed to stage 2.

2. GENTLY PAD to DRY the surface of the lesion using sterile hydrophilic TNT GAUZES. As soon as the gauze used to pad the wound appears saturated and/ or soiled, discard it and replace with a fresh one. Continue until the wound is completely dry and clean.




1. Are there eschars (dry, blackish crust - necrosis)?
If yes, autolytic debridement using Hyperoil® must be performed first of all to remove the eschars.

Either the OILY or the GEL formulation may be used on necrotic tissue (eschars). Apply these especially to periwound tissue in order to detach the eschars.
In fact, to allow Hyperoil® to remove the necrotic tissue, an opening must be created to let the product penetrate to the area between the eschars and the underlying lesion. To help create this opening, the eschars and periwound tissue must be softened. To achieve this, it is advisable to use a Hyperoil® GAUZE, in addition to the OILY or GEL formulation, to further soften the tissue. This will produce autolytic debridement. As soon as the eschar has detached a little at the margins, this allows Hyperoil® to reach the underlying periwound capillaries, the necrosis will detach within a very short period of time. The periwound margin can be cleaned using only saline solution or Hyperoil®.

2. Is there creamy material that is whitish, beige, yellow, greeny yellow, brown and or black in colour? Does the lesion have a bad smell?
If the answer to one or both of these question is "yes", it is advisable to apply the OILY formulation of Hyperoil® until these characteristics have disappeared and then proceed using the GEL formulation.

3. Is there exudate from the lesion (secretion of material or fluid)? How much?
If yes, use a secondary medication. The greater the exudate from the lesion is, the more absorbent this secondary medication should be.


The amount of Hyperoil® to apply is determined according to the size of the lesion and the STAGE that the lesion is at. e.g.: for a 10 см x 10 см lesion at the CLEANSING STAGE use:

  • for sprays (oily or gel) -> approx. 3 puffs
  • for droppers (50ml oil) -> 2 pipettes
  • if using a tube of GEL, apply enough product to cover the whole surface of the lesion with a very thin layer.
  • if using Hyperoil® GAUZES:
    • 1 gauze or, if the lesion is a quite deep, 2 gauzes folded to form two layers, side-by-side so as to cover the whole lesion.
    • if the lesion is very deep use 4 Hyperoil® GAUZES, folded into 4 layers, side-by-side so as cover the entire lesion.

In the subsequent STAGES of the lesion:

GRANULATION -> halve the quantity

REEPITHELIALIZATION -> reduce to a third

Hyperoil® GAUZES are excluded from this reduction as a quantity sufficient to cover the entire area of the lesion, including part of the periwound border, must always be used.

In order to medicate with Hyperoil® correctly, (in all of its formulations) a thin layer of the product left on the surface of the lesion is sufficient. This layer does not need to be even.

How to apply the various formats:

Hyperoil® in SPRAY format (OILY or GEL): after spraying the correct amount of product onto the lesion, spread it out with your finger. Take care to spread the product across the entire surface of the lesion as well as onto the healthy periwound skin.


Hyperoil® OILY formulation in DROPPER format:
after applying the product to the lesion as evenly as possible, spread it out with your finger. Take care to spread the product across the entire surface of the lesion as well as onto the healthy periwound skin.


Hyperoil® in GEL or CREAM GEL in a tube: apply the product to your fingers then spread it evenly across the entire surface of the lesion as well as onto the healthy periwound skin. The product is fully absorbed and is not greasy.


It is better to remove the Hyperoil® GAUZES from the packaging using tweezers. If no tweezers are available, use your hands. However, remember that the box must be closed quickly and securely to prevent the gauzes from drying out. Generally speaking, Hyperoil® GAUZES should be folded into two layers for moderately superficial lesions and into four layers for deeper lesions. They must cover (and, if necessary, fill) the entire surface of the lesion, preferably also extending beyond the periwound margin. If the lesion is very shallow, Hyperoil® GAUZES may also be applied without being folded. Individually-packaged Hyperoil® GAUZES in boxes of 10 will be available soon.


For more severe lesions, it is useful to apply Hyperoil® OILY or GEL formulation as well as Hyperoil® GAUZES to help the lesion to heal through gradual, constant release of the product. Hyperoil® GAUZES must then be held in place with sterile TNT gauzes, secured with breathable dressing tapes, which, if necessary, can in turn be secured with bandages or other supports.

Sometimes, the location of the wound is not conducive to the product staying in place. This problem is more frequently encountered with the OILY formulation than with the GEL formulation, which more easily remains adhered to the lesion. If in doubt as to whether Hyperoil® (either GEL or OILY), may not stick to the lesion, it is advisable to also apply Hyperoil® GAUZES, as described in the indications for applying the various formats. For example, for bedsores it is useful to fill the cavity of the lesion with Hyperoil® GAUZES or sterile TNT gauzes soaked in OILY or GEL formulation.




The best secondary medications to use to cover the lesion following application of the required Hyperoil® formulations are:




  • on lesions with low or a moderate degree of secretion it is sufficient to use TNT GAUZES
  • on lesions with a great deal of secretion, absorbent CUSHIONS or COMPRESSES must be used

If in doubt, apply the ABSORBENT COMPRESSES or CUSHIONS and then add one or more TNT GAUZES followed by a BANDAGE to hold the dressing in place.

Next, proceed as follows:

  • Take enough medication to cover the whole lesion:
    • TNT GAUZES if there is a low or moderate amount of exudate from the lesion.
    • ABSORBENT CUSHIONS or COMPRESSES if there is a large amount of exudate from the lesion.
  • Use a breathable dressing tape to secure the TNT GAUZES or ABSORBENT medications to the skin a suitable distance from the lesion.
  • Apply the cohesive elastic crepe BANDAGE to prevent the medication from moving but not so tight as to impede blood circulation.
  • In certain types of lesion and depending on the indications of the health professional, Hyperoil®, together with the gauzes and protective/absorbent medications required, may be fastened using compressive bandages and socks.
  • If the GAUZES and/ or the BANDAGE as a whole are very wet and/or the plasters do not adhere to the skin, it is only necessary to replace the gauzes and dressing strips; you do not need to reapply Hyperoil®.
  • If there are ulcers, permanently bandage and renew the dressing each time the medication is applied, for faster healing.
  • To COVER, and therefore protect and/ or absorb, it is best to use fine weave gauzes whilst to CLEANSE it is theoretically better to use gauzes with a more open weave.
  • Hyperoil® is effective as a moisturiser and for the treatment of deepithelialisation as well as skin that has become dry due to bandaging. Apply to the affected areas, in GEL or cream GEL formulation, each time the bandage is reapplied.

In many cases, use of Hyperoil® can reduce or obviate the need for local antibiotic therapy and reduce the dose and duration of systemic antibiotic therapy.


Adequate perfusion of the skin is required for Hyperoil® to work correctly. The device is ineffective where tissue hypoxia is less than 30mmHg of O2.


Application of the product, in all formulations,
may lead to a temporary sensation of burning, itching or reddening around the damaged area. However, the product will gradually reduce the pain at the site of the lesion and promoting healing.


Bleeding in a lesion that does not heal easily is a very positive sign as it means
that a chronic lesion is in the process of returning to an acute lesion which responds to primary healing.

Start seeing results now!


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